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3 Dec 2020

Cytopoint licence extends to treat pruritus

Zoetis announces antibody therapy, already approved for treatment of clinical manifestations of atopic dermatitis in dogs, now has wider application.

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Cytopoint licence extends to treat pruritus

Regulators have extended the licence for Zoetis’ canine dermatitis product Cytopoint (lokivetmab) to cover treatment of pruritus associated with allergic dermatitis – an addition to the original claim for atopic dermatitis.

Cytopoint is an injectable monoclonal antibody therapy for dogs that targets and neutralises the cytokine IL-31, a key mediator of allergic itch.

It means vets can now offer the rapid, long-lasting itch relief to more dogs suffering from pruritic skin disease.

Claim

The new claim was granted following additional research in the form of randomised, double-masked, multicentred, placebo-controlled study that looked at Cytopoint’s efficacy and safety for treatment of pruritus associated with allergic dermatitis in client-owned dogs.

The study showed it significantly desecrated pruritus and improved skin lesions.

Common condition

Allison Henry, product manager companion animal dermatology at Zoetis UK, said: “Allergic dermatitis is one of the most common skin conditions in dogs. The associated clinical signs – including scratching, hair loss and skin lesions – are disruptive for the dog, impacting quality of life and that of its owner. Allergic skin disease is one of the most frequent reasons owners present their dog to a veterinarian.

Zoetis said the sustained duration of action of Cytopoint makes it better suited to long-term management of pruritus, particularly when administering tablets is a challenge. It also has no restrictions on age and comorbidities.

A video on Cytopoint is available below. For further information, speak to a Zoetis account manager.